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Silver in PDB 4x89: Navms Voltage-Gated Sodium Channal Pore and C-Terminal Domain Soaked with Silver Nitrate

Protein crystallography data

The structure of Navms Voltage-Gated Sodium Channal Pore and C-Terminal Domain Soaked with Silver Nitrate, PDB code: 4x89 was solved by C.E.Naylor, C.Bagneris, B.A.Wallace, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 45.25 / 2.62
Space group C 2 2 21
Cell size a, b, c (Å), α, β, γ (°) 80.000, 329.240, 80.020, 90.00, 90.00, 90.00
R / Rfree (%) 22.8 / 24.5

Other elements in 4x89:

The structure of Navms Voltage-Gated Sodium Channal Pore and C-Terminal Domain Soaked with Silver Nitrate also contains other interesting chemical elements:

Sodium (Na) 7 atoms

Silver Binding Sites:

The binding sites of Silver atom in the Navms Voltage-Gated Sodium Channal Pore and C-Terminal Domain Soaked with Silver Nitrate (pdb code 4x89). This binding sites where shown within 5.0 Angstroms radius around Silver atom.
In total only one binding site of Silver was determined in the Navms Voltage-Gated Sodium Channal Pore and C-Terminal Domain Soaked with Silver Nitrate, PDB code: 4x89:

Silver binding site 1 out of 1 in 4x89

Go back to Silver Binding Sites List in 4x89
Silver binding site 1 out of 1 in the Navms Voltage-Gated Sodium Channal Pore and C-Terminal Domain Soaked with Silver Nitrate


Mono view


Stereo pair view

A full contact list of Silver with other atoms in the Ag binding site number 1 of Navms Voltage-Gated Sodium Channal Pore and C-Terminal Domain Soaked with Silver Nitrate within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Ag305

b:0.3
occ:1.00
O C:PRO187 2.9 28.8 1.0
OE1 B:GLU159 3.5 50.9 1.0
CB C:ASN190 3.5 30.7 1.0
CD B:GLU159 3.7 65.3 1.0
CG2 C:VAL191 3.7 32.4 1.0
OE2 B:GLU159 3.8 54.6 1.0
C C:PRO187 3.9 28.0 1.0
CZ C:PHE157 4.0 25.9 1.0
O A:HOH407 4.1 26.7 1.0
CE1 C:PHE157 4.1 26.8 1.0
ND2 C:ASN190 4.1 51.6 1.0
CA C:PRO187 4.2 25.0 1.0
CG C:ASN190 4.4 59.4 1.0
CG B:GLU159 4.5 45.2 1.0
CA C:ASN190 4.6 28.1 1.0
CB C:PRO187 4.6 26.1 1.0
N C:VAL191 4.6 29.1 1.0
OD1 A:ASN190 4.6 58.1 1.0
C C:ASN190 4.7 34.1 1.0
CB C:VAL191 4.9 32.0 1.0

Reference:

C.E.Naylor, C.Bagneris, P.G.Decaen, A.Sula, A.Scaglione, D.E.Clapham, B.A.Wallace. Molecular Basis of Ion Permeability in A Voltage-Gated Sodium Channel. Embo J. V. 35 820 2016.
ISSN: ESSN 1460-2075
PubMed: 26873592
DOI: 10.15252/EMBJ.201593285
Page generated: Sun Jul 6 20:49:12 2025

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