Silver in PDB 7c17: The Cryo-Em Structure of E. Coli Cuer Transcription Activation Complex with Fully Duplex Promoter Dna

Enzymatic activity of The Cryo-Em Structure of E. Coli Cuer Transcription Activation Complex with Fully Duplex Promoter Dna

All present enzymatic activity of The Cryo-Em Structure of E. Coli Cuer Transcription Activation Complex with Fully Duplex Promoter Dna:
2.7.7.6;

Other elements in 7c17:

The structure of The Cryo-Em Structure of E. Coli Cuer Transcription Activation Complex with Fully Duplex Promoter Dna also contains other interesting chemical elements:

Magnesium	(Mg)	1 atom
Zinc	(Zn)	2 atoms

Silver Binding Sites:

The binding sites of Silver atom in the The Cryo-Em Structure of E. Coli Cuer Transcription Activation Complex with Fully Duplex Promoter Dna (pdb code 7c17). This binding sites where shown within 5.0 Angstroms radius around Silver atom.
In total only one binding site of Silver was determined in the The Cryo-Em Structure of E. Coli Cuer Transcription Activation Complex with Fully Duplex Promoter Dna, PDB code: 7c17:

Silver binding site 1 out of 1 in 7c17

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Silver Binding Sites List in 7c17

Silver binding site 1 out of 1 in the The Cryo-Em Structure of E. Coli Cuer Transcription Activation Complex with Fully Duplex Promoter Dna

Mono view

Stereo pair view

A full contact list of Silver with other atoms in the Ag binding site number 1 of The Cryo-Em Structure of E. Coli Cuer Transcription Activation Complex with Fully Duplex Promoter Dna within 5.0Å range:

probe	atom	residue	distance (Å)	B	Occ
G:Ag201 b:0.5 occ:1.00	SG	G:CYS120	2.2	0.5	1.0
	SG	G:CYS112	2.3	0.4	1.0
	O	H:ARG75	2.6	0.9	1.0
	O	G:ASP119	3.2	0.5	1.0
	C	H:ARG75	3.4	0.9	1.0
	CB	G:CYS120	3.6	0.5	1.0
	CB	G:CYS112	3.7	0.4	1.0
	C	G:ASP119	3.9	0.5	1.0
	N	H:HIS76	4.0	1.0	1.0
	OG	H:SER77	4.1	0.9	1.0
	CA	H:HIS76	4.1	1.0	1.0
	CA	G:CYS120	4.1	0.5	1.0
	O	G:SER117	4.1	0.1	1.0
	N	H:SER77	4.3	0.9	1.0
	CB	H:ARG75	4.3	0.9	1.0
	N	G:CYS120	4.3	0.5	1.0
	CA	H:ARG75	4.3	0.9	1.0
	C	H:HIS76	4.5	1.0	1.0
	N	G:ASP119	4.7	0.5	1.0
	N	H:ARG75	4.7	0.9	1.0
	OG	G:SER117	4.8	0.1	1.0
	CB	H:SER77	4.9	0.9	1.0
	CA	G:ASP119	5.0	0.5	1.0

Reference:

C.Fang, S.J.Philips, X.Wu, K.Chen, J.Shi, L.Shen, J.Xu, Y.Feng, T.V.O'halloran, Y.Zhang. Cuer Activates Transcription Through A Dna Distortion Mechanism. Nat.Chem.Biol. 2020.
ISSN: ESSN 1552-4469
PubMed: 32989300
DOI: 10.1038/S41589-020-00653-X

Page generated: Wed Jul 10 08:40:04 2024

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